The Tag-lite® ligand binding assay is a homogeneous alternative to radioligand binding assays for HTS and compound profiling. The assay is based on the competition between the fluorescent ligand and compound.
Profiling of GPCR targeting drugs using Tag-lite technology Belhocine A, Veglianese P, Hounsou C, Dupuis E, Durroux T, Goudet C, Trinquet E and Pin JP - Team Cell2Lead, INSERM, University of Montpellier, Institute of Functional Genomics, Montpellier, France. Cisbio Bioassays, Codolet, France. Dulbecco Telethon Institute, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy. 5th HTRF Symposium, Avignon, France