Cisbio Bioassays has developed a comprehensive platform of universal and enzyme-specific assays for monitoring key oncology targets including kinases, ATPases, ubiquitin and heparanase.

HTRF® KinEASE™ is a universal platform for Serine/Threonine and Tyrosine kinases. These reagents use a series of biotinylated universal substrates and a single Mab.

HTRF® Transcreener® ADP assay, is a universal solution for kinases and ATPases. This assay is a homogeneous non-radioactive and enzyme-free detection solution to measure the generation of ADP.

Cisbio Bioassays's Kinase Toolbox contains tools such as labeled anti-phosphoresidue antibodies for measuring kinase-specific enzyme activity.

Kinases and ATPases are just one area of interest in Oncology research. Additional oncology-related assays developed by Cisbio Bioassays include HTRF Ubiquitin and Heparanase Assays as well as HTRF Toolbox Reagents for the study of cell signaling, cell cycle regulation, biomarker discovery, ligand binding, receptor activation and induction of second messengers.