GPCR dimer assays with Tag-lite® technology
Plasmids are designed to express the SNAP-Tag at the N-terminal position of the GPCR. All these targets are also available on demand with the CLIP-Tag for GPCR heterodimer studies.
Applications
- Receptor deorphanization A GPCR could be deorphanized by a drug through the characterization of a GPCR heterodimeric complex.
- New GPCR targets to identify heterodimer specific drugs.
Cisbio can help develop your own GPCR dimer assay.
How to develop a GPCR dimer assay with Tag-lite
Reagents to order
Plasmids
- pSNAP-GPCR plasmids to transiently express the GPCR of interest
- pCLIP-GPCR plasmids for investigating GPCR heterodimers
- pSNAP & pCLIP plasmids to construct your own targets
Substrates
- Selection of three conjugate substrates for each SNAP- or CLIP-tag.
- Lumi4-Tb
- Green fluorophore
- Red fluorophore
- Tag-lite labeling medium, optimized medium for SNAP- and CLIP-tags labeling
For more information or To Place an Order:
Europe and other countries
+33(0)466 796 705
