Tag-lite® fluorescent ligand
Application to GPCR ligand binding assays
Cisbio Bioassays offers a comprehensive platform to develop HTRF ligand binding assays.
- pSNAP-GPCR plasmids to transiently express the GPCR of interest
- Tag-lite SNAP-Lumi4-Tb substrate to label the SNAP-Tag
- Tag-lite fluorescent ligands validated in a ligand binding assay
Features:
- Single technology and cellular platform for all GPCR assays
- Unique non-radioactive ligand binding assays
- Peptidic and non-peptidic fluorescent ligands
- High Specific Binding
- Low Non-Specific Binding with HTRF® technology
- Validated in a ligand binding assay on the Tag-lite appropriate target
- Miniaturization down to < 10µl
Tag-lite fluorescent ligands are proposed to develop a homogeneous ligand binding assay.
Click on the receptors in the table below for more information.
| Receptor family | Receptor |
| Adrenergic | Alpha 1A |
| Beta2 | |
| Angiotensin | AT1 |
| AT2 | |
| Bombesin | BB2* |
| Bradykinin | B1* |
| B2 | |
| Chemokine | CXCR4 |
| Cholecystokinin | CCK1 |
| CCK2 | |
| Dopamine | D2 |
| Endothelin | ETA* |
| ETB* | |
| GABA | GABA-B |
| Ghrelin | GHSR1 A |
| Receptor family | Receptor |
| Glucagon | GIPR |
| Histamine | H1 |
| Melanocortin | MC3 |
| MC4 | |
| MC5 | |
| Opioid | Mu opioid |
| Delta opioid | |
| Kappa opioid | |
| Tachykinin | NK1 |
| NK2 | |
| Vasoactive Intestinal Peptide | VPAC1 |
| Vasopressin/Oxytocin | V1a |
| V2 |
* Please contact us for more information
For more information or To Place an Order:
Europe and other countries
+33(0)466 796 705
