GPCR Solutions

Comprehensive HTRF cellular platform


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IP-One kits, Gq second messenger accumulation assays
Cellulerk, a new kit to explore transduction pathway
cAMP kits gi gs second messenger accumulation assays
Cell surface receptor studies and functional assays.

GPCR investigation is among the top priorities in drug discovery research.

Cisbio has supported this area for many years by bringing regularly cutting edge assays and technologies fitted for receptor characterization and for compounds screening and lead optimization

Cisbio expands its offers for functional readouts (second messenger accumulation assays: cyclic-AMP & IP-One) with Cellul'erk, a new assay which allows detection of phosphorylated ERK directly in cells.

The new Tag-lite™ cell-surface receptor platform means Cisbio Bioassays now provides reagents and technology to address the latest evolution in the GPCR drug discovery field.

Features:
  • Single technology and cellular platform for all GPCR assays
  • Unique non-radioactive ligand binding assays
  • Miniaturization down to < 10µl

GPCR functional assays

Second messenger accumulation kits
Gi/Gs
Gq
Phosphorylated ERK1/2 detection
GI/s/q