GPCR Solutions

Comprehensive HTRF cellular platform


print
IP-One
Cellulerk
cAMP
Cell surface receptor studies and functional assays.

GPCR investigation is among the top priorities in drug discovery research.

Cisbio has supported this area for many years by bringing regularly cutting edge assays and technologies fitted for receptor characterization and for compounds screening and lead optimization

Cisbio expands its offers for functional readouts (second messenger accumulation assays: cyclic-AMP & IP-One) with Cellul'erk, a new assay which allows detection of phosphorylated ERK directly in cells.

The new Tag-lite™ cell-surface receptor platform means Cisbio Bioassays now provides reagents and technology to address the latest evolution in the GPCR drug discovery field.

Features:
  • Single technology and cellular platform for all GPCR assays
  • Unique non-radioactive ligand binding assays
  • Miniaturization down to < 10µl
  • GPCR cell-lines

GPCR functional assays

Second messengers accumulation kits
Gi/Gs
Gq
Phosphorylated ERK1/2 detection
GI/s/q