You are here : Home / Products / GPCRs / Tag-lite® cell lines

Tag-lite® cell lines

A unique multi-mode cellular platform to address the GPCR signaling network

This comprehensive cellular platform addresses the entire GPCR signaling network. Tag-lite cell lines are optimized to be combined with a portfolio of kits and reagents in highly selective ligand binding and receptor dimerization assays. This rapid and non-radioactive platform has been designed for a comprehensive investigation of receptor network signaling, while preserving the functionality of the receptor and the intracellular signaling pathways.

All the cell lines have been validated with HTRF® kits and reagents for ligand binding assay and at least 2 functional assays including cAMP, IP-One, phospho-Erk and internalization assays.

 

Features:

  • SNAP-GPCR stable cell lines
  • Single technology and cellular platform compatible with all GPCR classes and families

Applications:

  • Ligand binding assays
  • Second messenger accumulation assays with cAMP kits or IP-One kits
  • Phospho-Erk assays
  • Tag-lite internalization assays

 

Family Target Part # Binding
assay
Functionnal assays Product insert MSDS
cAMP or IP-One ERK Internalization
Adrenoceptor Beta2 C1SU1BETA2 - pdf pdf
Chemokine CCR1 C1SU1CCR1 pdf pdf
CCR5 C1SU1CCR5 - pdf pdf
CXCR4 C1SU1CXCR4 - pdf pdf
CXCR7 C1SU1CXCR7 - - pdf pdf
Cholecystokinin CCK1 C2SU1CCK1 pdf pdf
CCK2 C1SU1CCK2 pdf pdf
Dopamine D2 C2SU1D2 - pdf -
EGFR EGFR C1SU1EGRF1 - - -
Endothelin ETB C1PU1ETB - pdf -
Ghrelin GHSR1 A C1SU1GHSR1A - pdf pdf
Melanocortin MC4 C1SU1MC4 - pdf pdf
Opioid Delta opioid C2SU1DOP pdf pdf
Mu opioid C2SU1MOP pdf pdf
Tachykinin NK1 C1SU1NK1 - pdf pdf
Vasoactive Intestinal Peptide VPAC1 C2SU1VPAC1 pdf pdf
Vasopressin/Oxytocin V1a C1PU1V1A - pdf pdf
V2 C1PU1V2 - pdf pdf

 





© 2012 Cisbio.com - All Rights Reserved