Epigenetic screening

Bringing the proven throughput, specificity and robustness of HTRF technology to your epigenetic screening assays.
Rapid advancements have been made in understanding the key role epigenetic modifications play in regulating cell activity and their implications on cell health and disease progression. This knowledge led to a growing interest in exploring epigenetic enzymes and proteins, such as histone methyltransferases (HMT), demethylases (HDMT), deacetylases (HDAC) and acetylases (HAT) as drugable targets. Cisbio Bioassays offers a line of HTRF epigenetic toolbox reagents and kits for reliable, high throughput screening and investigation of epigenetic targets. In addition to our HTRF product offering, Cisbio scientists provide custom labeling and assay development services that create new and innovative epigenetic screening approaches including cellular screening, full histone assays, protein:protein binding assays and more.
Epigenetic toolbox reagents
A panel of MAbs to detect specific methylation and demethylation of Histone H3
Human SIRT1 assay
An HTRF ready-to-use assay kit for measuring SIRT1 deacetylase activity
Ubiquitin assay toolbox
A line of HTRF reagents for monitoring protein ubiquitination
Universal Methyltransferase Assay
A high throughput, universal assay for detection of histone methyltransferase activity
