BMG LABTECH Readers

The high performance microplate readers from BMG LABTECH are excellent HTRF® detection platforms for Cisbio Bioassays reagents. The RUBYstar is a dedicated microplate reader for high-end HTRF measurements. The PHERAstar microplate reader series includes the PHERAstar Plus and the PHERAstar FS. These high-end HTS multidetection microplate readers provide uncompromising sensitivity, speed and dynamic range. The PHERAstar series supports endpoint readings as well as kinetic measurements and well scanning. They are built around a multifunctional assay platform with multiple excitation sources and four PMTs for optimal performance in any assay mode. These readers are the only microplate readers on the market that can capture TR-FRET decay curves in real-time for assay optimization. Moreover, sequential dual excitation, selected matched pairs of PMTs, simultaneous dual emission detection, and ratiometric calculations are important features, giving unrivalled HTRF performance. The FLUOstar Omega and POLARstar Omega are mid-throughput life science readers certified for HTRF. The Advanced TRF Optic Head enables the Omega readers to perform HTRF assays. All BMG LABTECH readers can be integrated into robotic platforms for HTS work or can be equipped with BMG LABTECH's 50 plate Stacker for stand-alone use.

• Multi-detection reader (HTRF, TR-FRET, TRF, FI, FP, FRET, luminescence, UV/Vis absorbance spectra from 220 - 1000 nm, and high-end AlphaScreen®/AlphaLISA®)
• High energy xenon flashlamp excitation
• Dedicated 337 nm nitrogen laser excitation for HTRF/TR-FRET assays
• Four PMT system, two TR-FRET/ HTRF dedicated PMTs
• Simultaneous dual emission detection for all modes including HTRF
• Z-axis focus with 0.1 mm resolution for optimal results in all modes
• TR-FRET decay curve monitoring in real time with 2 µsec resolution
• Advanced top and bottom reading
• High resolution cell layer scanning
• Onboard smart reagent injectors
• Plate formats supported: 6- to 3456- well microplates
• 45°C incubation standard for precise temperature control

• HTS Instrument Discovers Low Affinity Inhibitors of the Inositol Phosphate (IP) Signaling Pathway (application note)
• More information on BMG LABTECH's website

• Multi-detection reader (HTRF,TR-FRET, TRF, FI, FP, FRET, luminescence, UV/Vis absorbance, and high-end AlphaScreen/AlphaLISA)
• High energy xenon flashlamp excitation
• Four PMT system, two TR-FRET/ HTRF dedicated PMTs
• Simultaneous dual emission detection for all modes including HTRF
• Z-axis focus with 0.1 mm resolution for optimal results in all modes
• TR-FRET decay curve monitoring in real time with 2 µsec resolution
• Plate formats supported: 6- to 1536- well microplates
• 45°C incubation standard for precise temperature control

• HTRF IP-One Terbium-based assay performed on BMG LABTECH's PHERAstar Plus (application note)
• GPCR Activation is Measured with Cisbio’s cAMP and IP-One HTRF HTplex™ Cell-based Assay (application note)
• Functional Screening of recombinant CHO-M1 cells using the PHERAstar from BMG LABTECH (application note)
• Cisbio´s HTRF Cortisol assay performed on the PHERAstar (applicaton note)
• More information on BMG LABTECH's website

• Multidetection Reader (HTRF, TR-FRET, TRF, FI, FP, luminescence, UV/Vis absorbance spectrum from 220 - 1000 nm, and AlphaScreen/AlphaLISA)
• High energy flashlamp excitation
• Simultaneous dual emission
• Onboard smart injectors
• Plate formats supported: 6- to 1536- well microplates

• More information on BMG LABTECH's website

• Multidetection Reader (HTRF, TR-FRET, TRF, FI, luminescence, UV/Vis absorbance spectrum from 220 - 1000 nm, and AlphaScreen/AlphaLISA)
• High energy flashlamp excitation
• Onboard smart injectors
• Plate formats supported: 6- to 1536- well microplates

• More information on BMG LABTECH's website

RUBYstar:

• HTRF on RUBYstar (application note)